Just to throw my own experience in the mix. I tried the AIO and standard versions of Nextcloud and found them to be flakey and slow. But I felt compelled to keep trying. That’s when I found NextcloudPi. I’ve installed it on a Pi4 running from an external SSD and it’s been rock solid. I believe that version is no longer in development though and I primarily use it as a sync platform for various apps rather than using the web apps directly.
And just to be contrary, have you looked at Seafile? It’s stupid fast and stable but some features are hidden behind a paywall if you have more than 3 users (community vs pro). Their documentation is poor, and the data is stored in Git-lik chunks on the server. All of which can be a deal breaker for some. The external storage feature works, but for a newb like me, it was a bear to get running.
Does Technitium support DNS rewrites like Adguard Home?