Noo

On the DAW, the three are good, I use Ardour cause it’s a free software, but I’ve been told the other two are good, specially for people coming from ableton who want something close. Ardour is really a old-fashioned saw like pro-tools.

Check Librazik it’s a distro based on debian made for musicale production.

I’d say you don’t need a specific distro for what you want to do : a Debian or Arch with KDE could do the trick, but I would recommend to use a lighter desktop environment like Xfce. You may not like it coming from mac but it will preserve machine resources for your audio work.

Ardour runs pretty much on it’s own on any distro, you can still do some conf, I suggest to go to linuxmao.fr the website is mostly in French but have a lot of configuration documentation.

This audio interface will not be an issue as it’s plug and play on Linux since a while now.

Poppy Linux should do.