National institutions are going to fail as Trump reclassifies civil servants as political appointments. Only those loyal to trump will remain.
There will be a substantial brain drain as people with means and motivation leave the US for elsewhere. This will mostly be college educated people who lean center to left of center. There is likely to be an influx of political refugees to New Zealand, western Europe, and the Nordic countries. This means leftists who can’t leave will be stuck here. This will push the US further right, and push the other countries further right because the people leaving aren’t as far left as they think they are.
Business regulations will be lax, and enforcement will be diminished. OSHAs budget will be cut even further, leaving states to manage workplace safety. Businesses will migrate towards red states where operations are cheaper.
Blue states will start banding together on their own enforcement systems for everything that the federal government used to manage. We already see this to some extent with manufacturers tending to comply with California regulations for nationwide stuff.
I would also recommend not eating your fingers, they tend to not grow back.